Pakistan are due to arrive in England on Sunday, with a final round of coronavirus testing to determine who can make the trip.
A total of 10 from an initial squad of 29 have already tested positive for COVID-19 and were set to join those who have previously received the all-clear in proceeding to a second screening round.
It is thought 10 positive cases – Haider Ali, Haris Rauf, Shadab Khan, Fakhar Zaman, Imran Khan, Kashif Bhatti, Mohammad Hafeez, Mohammad Hasnain, Mohammad Rizwan and Wahab Riaz – will not be on the charter flight from Lahore to Manchester, but the Pakistan Cricket Board will confirm their travelling group on Saturday.
Reserves Bilal Asif, Imran Butt, Musa Khan and Mohammad Nawaz could make the trip in their stead, provided they test negative.
On arrival in England the squad will head to Blackfinch New Road, using Worcestershire’s ground as their base and training camp during a mandatory 14-day quarantine.
The plan is then to move to Derbyshire’s Incora County Ground on July 13 to begin internal warm-up matches ahead of three Tests and three Twenty20s against England.
Stokes will cover regular captain Joe Root, who misses the first Test as he attends the birth of his second child.
Holder has led the West Indies for nearly five years.
Last month, Vikram Solanki took the reins at Surrey to become the only head coach among the 18 first-class counties from a diverse background.
A game-wide anti-discrimination charter and code will be introduced.
Stokes will be skipper for the first Test against the West Indies, and Root took the time to write a short note to his stand-in.
A majority vote was reached at a meeting of first-class counties chairmen on Tuesday.
The Durham man tiptoed around ICC rules on overt political statements but made clear the occasion would not go unmarked by England.
Contests between the two sides have seen a number of record-breaking performances.
The former England spinner insists Test cricket can survive a summer without crowds.
The pair will go head to head this week when the first Test between England and West Indies gets under way in Southampton.